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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
18.5 DPC

12 matching records from 12 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Wnt4  wingless-type MMTV integration site family, member 4   (Synonyms: Wnt-4)
Results  Reference
1J:199581 Bohnenpoll T, Bettenhausen E, Weiss AC, Foik AB, Trowe MO, Blank P, Airik R, Kispert A, Tbx18 expression demarcates multipotent precursor populations in the developing urogenital system but is exclusively required within the ureteric mesenchymal lineage to suppress a renal stromal fate. Dev Biol. 2013 Aug 1;380(1):25-36
1*J:248190 Chen K, Quan H, Chen G, Xiao D, Spatio-temporal expression patterns of Wnt signaling pathway during the development of temporomandibular condylar cartilage. Gene Expr Patterns. 2017 Nov;25-26:149-158
1J:201586 Das A, Tanigawa S, Karner CM, Xin M, Lum L, Chen C, Olson EN, Perantoni AO, Carroll TJ, Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation. Nat Cell Biol. 2013 Sep;15(9):1035-44
1J:295217 Drake KA, Chaney CP, Das A, Roy P, Kwartler CS, Rakheja D, Carroll TJ, Stromal beta-catenin activation impacts nephron progenitor differentiation in the developing kidney and may contribute to Wilms tumor. Development. 2020 Jul 31;147(21):dev189597
1J:296650 England AR, Chaney CP, Das A, Patel M, Malewska A, Armendariz D, Hon GC, Strand DW, Drake KA, Carroll TJ, Identification and characterization of cellular heterogeneity within the developing renal interstitium. Development. 2020 Aug 14;147(15):dev190108
1J:80420 Heikkila M, Peltoketo H, Leppaluoto J, Ilves M, Vuolteenaho O, Vainio S, Wnt-4 deficiency alters mouse adrenal cortex function, reducing aldosterone production. Endocrinology. 2002 Nov;143(11):4358-65
1J:242320 Kosfeld A, Brand F, Weiss AC, Kreuzer M, Goerk M, Martens H, Schubert S, Schafer AK, Riehmer V, Hennies I, Brasen JH, Pape L, Amann K, Krogvold L, Bjerre A, Daniel C, Kispert A, Haffner D, Weber RG, Mutations in the leukemia inhibitory factor receptor (LIFR) gene and Lifr deficiency cause urinary tract malformations. Hum Mol Genet. 2017 May 01;26(9):1716-1731
1J:118250 Mahoney ZX, Sammut B, Xavier RJ, Cunningham J, Go G, Brim KL, Stappenbeck TS, Miner JH, Swat W, Discs-large homolog 1 regulates smooth muscle orientation in the mouse ureter. Proc Natl Acad Sci U S A. 2006 Dec 26;103(52):19872-7
1*J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372
1*J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1J:334527 Weiss AC, Blank E, Bohnenpoll T, Kleppa MJ, Rivera-Reyes R, Taketo MM, Trowe MO, Kispert A, Permissive ureter specification by TBX18-mediated repression of metanephric gene expression. Development. 2023 Mar 15;150(6):dev201048
1J:300975 Weiss AC, Rivera-Reyes R, Englert C, Kispert A, Expansion of the renal capsular stroma, ureteric bud branching defects and cryptorchidism in mice with Wilms tumor 1 gene deletion in the stromal compartment of the developing kidney. J Pathol. 2020 Nov;252(3):290-303

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory